Regulation of thermoelastic properties of concave-packaged DNA adsorption films and its relevant mic

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The packing patterns have close correlation with the thermoelastic properties of DNA adsorption films and the relevant detection signals of microcantilevers.In this paper,we investigate the influence of packing patterns on the thermoelastic properties of DNA adsorption films,the detection signals of microcantilevers and their temperature dependence.First,the Parsegian\'s empirical potential based on a mesoscopic liquid crystal theory is employed to describe the interaction energy among coarse-grained DNA cylinders;then,the thought experiment method and the force balance method of nonlinear elastic network nodes are combined to characterize the elastic modulus,prestress and thermal expansion coefficient of DNA adsorption films;finally,based on an effective macroscopic continuum model for DNA microbeam deformation,we study the microcantilever resonance frequency shifts caused by DNA adsorptions and the temperature effect on the microcantilever static deflections,respectively.Results show that,compared with the convex-packaged,the re-entrant honeycomb packing pattern endows DNA adsorption films with a larger adjustable range of the elastic modulus and prestress,so as to make DNA-microcantilevers having an enhanced dynamic detection signal whereas a weaker response to temperature variation.These results are expected to provide a new option for the regulation design of DNA composite materials and microbeam sensors.
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