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评价支气管动脉灌注化疗栓塞及CT导引下注入无水乙醇与超液化碘油双介入疗法治疗原发性肺癌的疗效。材料和方法:20例原发肺癌进行了单纯支气管动脉化疗,累计68次;20例进行了单纯支气管动脉化疗栓塞;另外40例均进行了双介入治疗,其中20例在支气管动脉化疗栓塞的同时进行了CT导引下注射无水乙醇与超液化碘油混合剂的介入治疗(PEI),化疗栓塞共计28次, 局部化疗40次。单纯化疗合并CT介入治疗20例,化疗共64次,以上40例进行的CT导引下注射无水乙醇与超液化碘油混合剂的介入治疗次数累计118次。结果:采用支气管动脉化疗栓塞(或化疗)合并 CT导引下注射无水乙醇的双介入疗法治疗有效率分别为 90%和80%,单纯支气管动脉化疗栓塞及单纯化疗的临床有效率分别为 70%和30%,双介入与单介入的有效率比较有显著性差异 (P<0.01)。随访双介入疗法治疗后的患者,3年生存率达到50%。结论:双介入疗法较单纯支气管动脉化疗或化疗栓塞治疗肺癌的临床有效率、生存率明显提高。
To evaluate the efficacy of double-interventional bronchial arterial infusion chemoembolization and CT-guided infusion of absolute ethanol and lipiodol for the treatment of primary lung cancer. Materials and Methods: Twenty primary lung cancers were treated with bronchial arterial chemotherapy alone for a total of 68 times; 20 patients underwent bronchial arterial chemoembolization alone; 40 patients underwent dual-interventional treatment, of whom 20 were concurrently treated with bronchial arterial chemoembolization. CT-guided interventional therapy (PEI) was performed with a mixture of absolute ethanol and lipiodol. Chemoembolization was performed 28 times and local chemotherapy was performed 40 times. Twenty patients underwent chemotherapy alone with CT intervention, and chemotherapy received a total of 64 times. The total number of interventional treatments for CT-guided injection of absolute ethanol and hyperlipidic lipiodol was more than 118 times. RESULTS: The use of bronchial arterial chemoembolization (or chemotherapy) combined with CT-guided ethanol injection was effective in 90% and 80%, respectively. The clinical efficacy of bronchial arterial chemoembolization and chemotherapy alone was 70. % and 30%, there was a significant difference between the efficiency of double intervention and single intervention (P<0.01). After the follow-up of double interventional therapy, the 3-year survival rate reached 50%. Conclusion: Double interventional therapy is more effective than bronchial arterial chemotherapy or chemoembolization in the treatment of lung cancer, and the survival rate is significantly improved.