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目的探讨硝普钠与酚妥拉明在冠状动脉粥样硬化性心脏病(CHD)合并心力衰竭患者急诊治疗中的应用价值。方法选取2014年1月至2015年1月沈阳急救中心收治的56例CHD合并心力衰竭急诊患者作为研究对象,按随机数字表法将其分为观察组与对照组,各28例。观察组患者给予硝普钠治疗,对照组患者采用酚妥拉明,比较两组患者临床治疗效果、治疗前后心功能改善情况。结果观察组患者治疗的总有效率明显高于对照组,差异有统计学意义(P<0.05);治疗后,观察组患者的左心室射血分数(LVEF)、左心室收缩末期内径(LVESD)明显高于对照组,左心室舒张末期内径(LVEDD)明显低于对照组,差异均有统计学意义(均P<0.05)。结论硝普钠治疗CHD合并心力衰竭急诊患者临床疗效优于酚妥拉明,可有效改善患者的心功能。
Objective To investigate the clinical value of sodium nitroprusside and phentolamine in the treatment of patients with coronary heart disease (CHD) complicated with heart failure. Methods Fifty-six patients with CHD complicated with heart failure admitted to Shenyang Emergency Center from January 2014 to January 2015 were selected as study subjects and divided into observation group and control group according to random number table method, with 28 cases in each group. Patients in the observation group were treated with sodium nitroprusside, and patients in the control group were treated with phentolamine. The clinical effects of the two groups were compared, and the improvement of cardiac function before and after treatment was compared. Results The total effective rate of observation group was significantly higher than that of control group (P <0.05). After treatment, left ventricular ejection fraction (LVEF), left ventricular end-systolic diameter (LVESD) (LVEDD) was significantly lower than that of the control group, the difference was statistically significant (all P <0.05). Conclusion Sodium nitroprusside is superior to phentolamine in the treatment of patients with CHD complicated with heart failure, which can effectively improve the cardiac function.