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恒河猴感染曼氏血吸虫尾蚴500条以上,3~4月常常出现相当的免疫力,使粪中虫卵减少、虫数减少,能抵抗激发感染。作者对感染600条及100条曼氏血吸虫尾蚴的恒河猴进行了比较。在开始的12周,两组动物平均每对成虫由粪便排出以及留在组织内的虫卵数相同,重感染组分别为186±25及5,700±1,200,轻感染组分别为128±40及4,800±300。在12~27周内,重感染组有2/3的成虫死亡,许多存活的成虫由大肠移行到小肠小静脉内,每对成虫由粪便排出的虫卵数减少,而轻感染组则无此现象。在第27周解剖时,重感染组的平均成对成虫发育率为18%,肝、小肠、大肠内的虫卵分布率分别为31±11,51±6及18±7,肝、肺、小肠、大肠每克组织内虫卵数分别为
Rhesus monkeys infected with Schistosoma mansoni cercariae 500 or more, 3 to 4 months often appear considerable immunity, reduce fecal eggs, reduce the number of insects, can resist the infection. The authors compared 600 rhesus macaques and 100 macaques of Schistosoma mansoni. In the first 12 weeks, the average number of eggs released from feces and remaining in the tissues in each group was the same for both groups, with severe infections of 186 ± 25 and 5,700 ± 1,200 respectively, with mild infections of 128 ± 40 and 4,800, respectively ± 300. In 12 to 27 weeks, 2/3 of the adults in the heavily infected group died, many of the surviving adults migrated from the large intestine to the small intestine venules, and the number of eggs excreted by each adult pair decreased as compared to those in the lightly infected group phenomenon. At the 27th week of dissection, the average pairwise adult development rate was 18% in the heavily infected group and 31 ± 11,51 ± 6 and 18 ± 7 in the liver, small intestine and large intestine respectively. The liver, lung, Small intestine, large intestine per gram of the number of eggs were