目的　研究一种结肠癌急性梗阻一期切除吻合的更简单、合理、安全的术中处理方法。方法　肠切开减压后 ,用左右手交替挤压法清洁肠道 ,不灌洗肠腔 ,使肠吻合后吻合口处持续有少许较稀薄的肠内容物通过。结果　采用本方法清洁肠道一期切除吻合的结肠癌急性梗阻 38例 ,术后无一例发生吻合口漏。结论　本方法在结肠癌急性梗阻一期切除吻合中应用 ,更为简单、合理、安全、可靠 Objective To study a simpler, more reasonable, and safe intraoperative treatment for primary resection and anastomosis of colon cancer. Methods After decompression with intestinal incision, the intestine was cleaned with alternating right and left hand squeezing, and the intestine was not lavaged. After the anastomosis of the intestine, a relatively thin and relatively thin intestinal content was passed through. Results In this study, 38 patients with acute obstruction of colon cancer who underwent primary resection and anastomosis of colon cancer were used. No postoperative anastomotic leakage occurred. Conclusion This method is applied to the primary resection and anastomosis of colon cancer with acute obstruction. It is more simple, reasonable, safe and reliable.