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骨形态形成蛋白受体IA(Receptor IA of bone morphogenetic protein,BMPR1 A)又名 ALK3。近年来,通过大量的实验方法包括基因敲除和转基因方法发现ALK3及其信号途径在心肌细胞分化和心脏发育过程中扮演重要的角色。本文就近年来研究发现ALK3信号传递途径与心脏发育的关系作一简要综述。
Bone morphogenetic protein receptor IA (Receptor IA of bone morphogenetic protein, BMPR1 A) also known as ALK3. In recent years, ALK3 and its signaling pathways have been found to play an important role in cardiomyocyte differentiation and cardiac development through numerous experimental methods including knockout and transgenesis. In this paper, recent research found that ALK3 signaling pathway and cardiac development for a brief review.