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卵巢组织冻融后移植或进行体外培养,在一定程度上可恢复卵巢内分泌功能和生育能力。冻融卵巢皮质切片自体原位和异位移植的研究有一定的进展,并开始应用于临床。移植前对冻融卵巢活力须进行评估,以保证移植的卵巢有一定数量的存活卵泡。对于带蒂卵巢移植来说,关键是改进血管灌注冷冻、复苏的方法。冻融卵巢自体移植如何尽快建立血供,减少缺血、缺氧对卵巢组织的损伤,提高卵泡存活率,以及冻融卵巢组织体外培养获得可供受精的卵母细胞的方法有待进一步研究。
Transplantation of ovarian tissue after freezing or thawing or in vitro culture, to some extent, can restore ovarian endocrine function and fertility. Freeze-thaw ovarian cortical autologous in situ and heterotopic transplantation transplantation has some progress, and began to be used in clinical. The vitality of the frozen-thawed ovary before transplantation should be assessed to ensure that there is a certain amount of viable follicles in the transplanted ovary. For pedicle ovarian transplantation, the key is to improve the vascular perfusion freezing and resuscitation methods. How to establish the blood supply as soon as possible to reduce the ischemia, hypoxic damage to ovarian tissue, improve the survival rate of ovarian follicles, and how to obtain fertilized oocytes in vitro by freezing-thawing ovarian autotransplantation remains to be further studied.