目的　动态观察高血压脑出血血肿冲洗液去甲肾上腺素 (NE)的变化及其意义。方法　行微创颅内血肿清除术的中、重度 (出血量 >30ml)高血压脑出血患者 6 0例 ,连续监测血肿冲洗液中NE的动态变化。结果　高血压脑出血发病 6小时血肿冲洗液中即已检测出NE ,并于 4 8～ 72小时达高峰值 ,此后逐渐降低。结论　高血压脑出血后出血灶及周边脑组织去甲肾上腺素含量增加 ,并参与其后的病理过程 ,其水平的变化与脑出血的转归有关 Objective To observe the changes of norepinephrine (NE) in hypertensive intracerebral hemorrhage hematoma and its significance. Methods Totally 60 patients with moderate and severe hypertensive intracerebral hemorrhage (hemorrhage> 30ml) underwent minimally invasive intracranial hematoma removal. The dynamic changes of NE in hematoma washing fluid were continuously monitored. Results Hypertensive intracerebral hemorrhage onset 6 hours hematoma rinse fluid that has been detected in NE, and in 48 to 72 hours reached its peak, then gradually decreased. Conclusion Hypertensive intracerebral hemorrhage after hemorrhage and peripheral brain tissue norepinephrine increased, and participate in the subsequent pathological process, the level of changes associated with the outcome of cerebral hemorrhage