Objective:To observe the clinical effects of the combined use of acupuncture and herbal medicine for treatment of chloasma. Methods: Totally 60 patients were randomly divided into a treatment group of 30 cases, treated by acupuncture and herbal medicine, and a control group of 30 cases, administered Vitamin C and Vitamin E. The clinical effects were observed. Results: The total effective rate of the treatment group is 93.3% better than that of the control group (76.7%), the difference was significant (P<0.01). Conclusion: Combined use of acupuncture and herbal medicine may yield definite therapeutic effects in treating chloasma patients.