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Riboflavin, which improves energy metabolism similarly to coenzymeQ10(CoQ10), is effective in migraine prophylaxis. We compared CoQ10 (3×100 mg/day) and plac ebo in 42 migraine patients in a double-blind,randomized, placebo-controlled t rial.CoQ10 was superior to placebo for attack-frequency, headache days and days -with-nausea in the third treatment month and well tolerated; 50%-responder -rate for attack frequency was 14.4%for placebo and 47.6%for CoQ10 (number-n eed- ed-to-treat: 3).CoQ10 is efficacious and well tolerated.
Riboflavin, which improves energy metabolism similarly to coenzyme Q10 (CoQ10), is effective in migraine prophylaxis. We compared CoQ10 (3 × 100 mg / day) and plac ebo in 42 migraine patients in a double-blind, randomized, placebo-controlled t rial .CoQ10 was superior to placebo for attack-frequency, headache days and days -with-nausea in the third treatment month and well tolerated; 50% -responder -rate for attack frequency was 14.4% for placebo and 47.6% for CoQ10 (number- n eed-ed-to-treat: 3) .CoQ10 is efficacious and well tolerated.