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目的比较中医治疗方式与西医治疗方式对控制儿童哮喘复发的效果,为儿童哮喘的治疗提供理论参考。方法选择某院近两年3～7岁哮喘儿童患者179例并随机分为两组,其中中医组儿童患者在哮喘间歇期采取黄芪辅助治疗,西医组儿童患者采取糖皮质激素的方法进行辅助治疗。对治疗效果进行评价并测定IL-2及IL-4水平,利用统计学方法进行数据分析。结果在间歇期利用黄芪进行治疗的儿童患者总有效率为86%,而利用糖皮质激素进行治疗的儿童患者总有效率为90%,两组之间不存在显著差异。两组治疗前后细胞因子IL-2及IL-4的均有不同程度的变化,两组间不存在显著差异,但黄芪治疗组的细胞因子更趋向于正常。结论利用中西医方式对儿童哮喘患者在间歇期进行治疗的效果不具有显著差异,然考虑到糖皮质激素的诸多副作用及儿童成长的需要,建议对该类患者哮喘间歇期采取黄芪进行辅助治疗。
Objective To compare the effect of traditional Chinese medicine (TCM) treatment and western medicine treatment on the control of childhood asthma recurrence and provide a theoretical reference for the treatment of childhood asthma. Methods A total of 179 asthmatic children aged 3 to 7 years old in a hospital in the past two years were selected and randomly divided into two groups. Astragalus-adjuvant treatment was given to children in TCM group during intermittent asthma, and glucocorticoid was used for adjuvant therapy in children in Western medicine group . The therapeutic effect was evaluated and the levels of IL-2 and IL-4 were measured, and the data were statistically analyzed. Results The total effective rate was 86% in pediatric patients treated with Astragalus during intermittent periods, while the total effective rate in children treated with glucocorticoid was 90%, with no significant difference between the two groups. Before and after treatment, the cytokines IL-2 and IL-4 both had different degrees of change, there was no significant difference between the two groups, but the astragalus treatment group cytokines tend to be more normal. Conclusions There is no significant difference between the two groups in the duration of intermittent treatment of asthma. However, taking into account the many side effects of glucocorticoids and the need of children’s growth, it is advisable to take astragalus for adjuvant treatment during the intermittent asthma period.