目的　探讨脑卒中后产生痴呆的危险因素和可能的机理。方法　对 186例脑卒中患者于入院时进行神经功能缺损程度评分和智能评估及头部CT检查。病程 3月后再进行智能评定。结果　脑卒中后痴呆的发生率为 32 5 %。痴呆的发生与年龄、文化程度、居住地、高血压、高血脂、卒中的部位及神经功能缺损的程度、糖尿病及冠心病关系密切 ,而与性别、吸烟、酗酒及卒中的性质关系不大 (P >0 0 5 )。结论　脑卒中后痴呆较为常见 ,是多因素作用的结果 Objective To explore the risk factors and possible mechanisms of dementia after stroke. Methods A total of 186 stroke patients were assessed for neurological deficits and their intelligence assessments and CT scans on admission. Course of disease after 3 months of intelligent assessment. Results The incidence of post-stroke dementia was 32.5%. The incidence of dementia is closely related to age, education level, place of residence, hypertension, hyperlipidemia, stroke site, degree of neurological deficit, diabetes and coronary heart disease, but not to sex, smoking, alcoholism and stroke P> 0 0 5). Conclusions Post-stroke dementia is more common and is the result of multiple factors