药用微型胶囊常由明胶或明胶-阿拉伯胶的混合物凝结制成,但明胶作原料时在操作上较难控制。本文介绍一种容易操作的乙酸苯二甲酸纤维素酯(Cellulose acetate phthalates,下简称 CAP)作微型胶囊。本法以非那西丁为囊心,使其混悬于 CAP的磷酸氢二钠溶液中,然后加入脱水剂硫酸钠溶液,即可使 CAP 析出并凝结在非那西丁的颗粒表面上,形成微型胶囊。 Medicinal microcapsules are often made by coagulating a mixture of gelatin or gelatin-acacia, but gelatin is more difficult to handle in operation. This article describes an easy-to-handle cellulose acetate acetate (Cellulose acetate phthalates, referred to as CAP) for microcapsules. This method to phenacetin as the center, make it suspended in the CAP of the disodium hydrogen phosphate solution, and then add the dehydrating agent sodium sulfate solution, you can make CAP precipitation and condensation in the phenacetin particles on the surface, Form microcapsules.