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To determine the impact of rapid advancement to more concentrated formula onwe ight gain and duration of hospitalization for infants after cardiac surgery. We performed a double-blinded, randomized trial of rapid advancement to higher ach ieved formula concentration for postoperative infants younger than 1 year of age . After transfer to the inpatientward from the critical care unit, infants were randomly assigned to rapid advancement to a higher achieved formula concentratio n (2-day transition) or usual care (5-day transition, lower concentration targ et). The adequacy of energy intake (expressed as the median percentage of the estimated energy r equirement) before discharge from the hospital was 98%in the intervention versu s 78%in the usual care group (P =.01). Before discharge, the median rate of we ight gain was greater in the rapid advancement (20 g/d) versus the usual care gr oup (loss of 35 g/d, P < .03). The median postoperative duration of stay on the cardiology inpatient unit was 5 days for the intervention versus 6 days for the usual care group (P < .05). Rapid advancement to higher achieved formula conce ntration significantly improved energy intake and weight gain and decreased dura tion of postoperative hospital stay in infants after cardiac surgery.
To determine the impact of rapid advancement to more concentrated formula onweight gain and duration of hospitalization for infants after cardiac surgery. We performed a double-blinded, randomized trial of rapid advancement to higher ach ieered formula concentration for postoperative infants younger than 1 year of age. After transfer to the inpatientward from the critical care unit, infants were randomly assigned to rapid advancement to a higher achieved formula concentratio n (2-day transition) or usual care (5-day transition, lower concentration targ et.) The adequacy of energy intake (expressed as the median percentage of the estimated energy r equirement) before discharge from the hospital was 98% in the intervention versu s 78% in the usual care group (P = .01). Before discharge, the median rate of we ight gain was greater in the rapid advancement (20 g / d) versus the usual care gr oup (loss of 35 g / d, P <.03). The median postoperative duration of stay on the cardiology inpatient un it was 5 days for the intervention versus 6 days for the usual care group (P <.05). Rapid advancement to higher achieved formula conce ntration significantly improved energy intake and weight gain and decreased dura tion of postoperative hospital stay in infants after cardiac surgery .