目的：探讨浆细胞性乳腺炎和肉芽肿性乳腺炎的临床特征及最佳治疗方案。方法回顾性分析80例浆细胞性乳腺炎或肉芽肿性乳腺炎患者的病史特点、辅助检查、病理特征、治疗方案及效果。结果80例患者经过手术治疗，全部治愈。伤口一期愈合21例。31例肿块较大者先药物治疗后再手术，其中1例术后1+个月复发，最终行皮下腺体单纯切除术。所有患者术后随访2~23个月，均未复发，对患侧乳房外形较满意者占96.25%(77/80)。结论综合粗针穿刺病理活检、超声、乳腺钼靶X线检查、磁共振(MR)及针吸细胞学等检查，基本能明确是浆细胞性乳腺炎还是肉芽肿性乳腺炎，而手术治疗是其治疗的根本方法。“,”ObjectiveTo investigate clinical features and optimal treatment regimen of plasma cell mastitis and granulomatous mastitis.MethodsA retrospective analysis was made on medical history characteristics, accessory examination, pathological features, treatment regimen and effects in 80 patients with plasma cell mastitis or granulomatous mastitis.ResultsAll 80 patients were cured after operation treatment, with 21 cases in stage one healing. Among 31 patients receiving drug therapy followed by operation for massive tumor, there was 1 recurrent case in postoperative 1+ month, which received subcutaneous glandular excision. Follow-up lasted for 2~23 months in all patients, and it showed no recurrence. Satisfaction rate of breast appearance was 96.25% (77/80).ConclusionComprehensive examination by coarse needle biopsy, ultrasound, breast molybdenum target x-ray examination, magnetic resonance (MR) and fine needle aspiration cytology can provide basic determination of plasma cell mastitis and granulomatous mastitis. Operation treatment is the fundamental treatment method.