Multiple|tone interference is a kind of narrow band interference appears in Direct Sequence (DS) Spread Spectrum (SS) communication system frequently that degrades the system performance. Most open literature studies on narrowband interference rejection assumed stationary SS signal and interference. SS signal and interference are modeled as cyclostationary and based on cyclostationary model, an interference rejection algorithm is proposed. Through computer simulation, it is shown that the performance of the SS system can be improved considerably after adopting this algorithm. Most open literature studies on narrowband interference rejection registered SS signal and interference. SS signal and interference are modeled as cyclostationary and based on cyclostationary model, an interference rejection algorithm is proposed. Through computer simulation, it is shown that the performance of the SS system can be improved considerably after adopting this algorithm.