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目的探讨rhGM-CSF与rhEGF对烧伤后患者残余创面愈合效果及愈合时间的影响。方法选取医院2014年2月-2015年9月收治烧伤后残余创面患者130例,以随机数字表法分为对照组和观察组各65例,分别采用rhEGF和rhGM-CSF治疗;比较2组患者临床疗效,创面愈合率及创面平均愈合时间等。结果观察组患者临床总有效率显著优于对照组,差异有统计学意义(P<0.05);观察组患者治疗后14d、21d及28d创面愈合率均显著高于对照组,差异有统计学意义(P<0.05);观察组患者创面平均愈合时间显著低于对照组,差异有统计学意义(P<0.05)。结论 rhGM-CSF用于烧伤后残余患者可有效提高创面愈合效果,缩短创面愈合时间,效果优于rhEGF。
Objective To investigate the effects of rhGM-CSF and rhEGF on wound healing and wound healing after burn wounds. Methods A total of 130 patients with post-burn residual wounds were selected from February 2014 to September 2015 in our hospital. The patients were divided into control group and observation group (n = 65) with rhEGF and rhGM-CSF respectively by random number table. Clinical efficacy, wound healing rate and average wound healing time. Results The total clinical effective rate in the observation group was significantly better than that in the control group (P <0.05). The wound healing rates in the observation group at 14d, 21d and 28d after treatment were significantly higher than those in the control group (P <0.05). The average wound healing time in the observation group was significantly lower than that in the control group (P <0.05). Conclusion The rhGM-CSF can effectively improve the wound healing effect and shorten the wound healing time after burn, and the effect is better than rhEGF.