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将在SV40早期启动子控制下表达狂犬病病毒糖蛋白的质粒(pSG5rab)转染小鼠L929成纤维细胞(t.L929.gp),可诱生免疫应答。本文介绍了一种筛选病毒蛋白诱生免疫应答能力的简单和廉价的方法。
The L929 fibroblasts (t.L929.gp) were transfected with a plasmid (pSG5rab) expressing the rabies virus glycoprotein under the control of the SV40 early promoter to induce an immune response. This article presents a simple and inexpensive way to screen for the ability of a viral protein to elicit an immune response.