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柳氮磺胺吡啶（ＳＡＳＰ）的活性部分是５—氨基水扬酸（５—ＡＳＡ），另一部分是磺氨吡啶（ＳＰ）。ＳＡＳＰ口服后以原形通过上消化道到达结肠后被细菌还原成为５—ＡＳＡ和ＳＰ。５—ＡＳＡ很少被吸收，直接起到局部治疗作用。而ＳＰ则产生副作用。徐子鹏等根据ＰＳＡ...
The active moiety of sulfasalazine (SASP) is 5-aminosalicylic acid (5-ASA) and the other is sulfapyridine (SP). After oral administration, SASP is reduced to 5-ASA and SP by bacteria after it reaches the colon through the upper digestive tract. 5-ASA is rarely absorbed, directly play a role in local treatment. The SP has side effects. According to PSA and other sub-PSA ...