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目的:总结毒鼠强(化学名称为4-甲基-2砜四胺)群体急性中毒的抢救与治疗经验。方法:对58例毒鼠强急性中毒患者进行反复洗胃、催吐,及早应用二巯基丙磺酸钠0.2g肌内注射,每6～8小时1次,连续使用2～4日,对重度中毒者予血液净化治疗;同时积极予以对症、支持治疗。结果:58例全部抢救成功,随访3个月无后遗症。结论:毒鼠强急性中毒症状复杂、凶险,对口服中毒者予立即反复洗胃、催吐,及早应用二巯基丙磺酸钠和血液净化是治疗的重要措施。
OBJECTIVE: To summarize the experience of rescue and treatment of acute toxicity of tetramine in rats (chemical name: 4-methyl-2-sulfonetetramine). Methods: Fifty-eight cases of acute poisoning in rats were subjected to repeated gastric lavage and vomiting. Intraperitoneal injection of sodium dimercaptopropane sulfonate 0.2 g intramuscularly once every 6 to 8 hours was used continuously for 2 to 4 days. Severe poisoning To the blood purification treatment; at the same time be actively symptomatic, supportive treatment. Results: All the 58 cases were successfully salvaged. There was no sequelae after 3 months of follow-up. Conclusion: Symptoms of tetramine poisoning are complicated and dangerous. For oral poisoning, gastric lavage and vomiting should be repeated immediately. Sodium dimercaptopropane sulfonate and blood purification are important measures for the treatment.