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采用紫外分光光度法(λmax237nm)对国产6个厂家的硝苯地平片进行体外溶出度考察。实验数据按威布尔分布模型进行拟合,得出溶出度参数。结果表明:各厂家的硝苯地平片的累积溶出存在显著性差异(P<0.01)。
UV spectrophotometry (λmax237nm) on domestic manufacturers of nifedipine tablets in vitro dissolution study. The experimental data were fitted according to the Weibull distribution model to obtain the dissolution parameters. The results showed that there was a significant difference in the cumulative dissolution of nifedipine tablets (P <0.01).