目的:观察扶正解毒祛瘀方联合化疗治疗非小细胞肺癌的临床疗效。方法:将60例非小细胞肺癌患者随机分为治疗组和对照组,治疗组30例采用扶正解毒祛瘀方联合紫杉醇加顺铂的化疗方案治疗,对照组30例单用紫杉醇加顺铂的化疗方案治疗。每3周为1个周期,两组均化疗1个周期后比较近期疗效、毒副反应、生活质量、体质量及免疫功能。结果:总有效率治疗组为53.3%,对照组为33.3%,组间比较,差异有统计学意义(P<0.05);治疗组骨髓抑制、胃肠道反应均明显低于对照组(P<0.05),生活质量(KPS)评分及细胞免疫功能均明显高于对照组(P<0.05),体质量则没有明显差异(P>0.05)。结论:扶正解毒祛瘀方联合化疗治疗非小细胞肺癌疗效较好,能有效减轻化疗后毒副反应,改善患者生活质量。 Objective: To observe the clinical effect of Fuzheng Jiedu Quyu Decoction combined with chemotherapy on non-small cell lung cancer. Methods: Sixty non-small cell lung cancer patients were randomly divided into treatment group and control group. The treatment group was treated with Fuzheng Jiedu Quyu Decoction combined with paclitaxel plus cisplatin. In the control group, 30 patients were treated with paclitaxel alone plus cisplatin Chemotherapy regimen. Every 3 weeks for a cycle, two groups were more effective after a cycle of chemotherapy, toxicity, quality of life, body weight and immune function. Results: The total effective rate was 53.3% in the treatment group and 33.3% in the control group. The differences between the two groups were statistically significant (P <0.05). The bone marrow suppression and gastrointestinal reaction in the treatment group were significantly lower than those in the control group (P < 0.05), KPS score and cellular immune function were significantly higher than those of the control group (P <0.05), while the body weight was not significantly different (P> 0.05). Conclusion: Fuzheng Jiedu Quyu Decoction combined with chemotherapy for non-small cell lung cancer has a good curative effect, which can effectively reduce side effects after chemotherapy and improve the quality of life of patients.