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实验结果表明,丹参能明显抑制正常及损伤肝细胞脂质过氧化反应,诱导细胞色素P450的合成,防止损伤肝细胞蛋白质、DNA、RNA、尿素及铜兰蛋白的降低,减轻肝毒物对体外培养肝细胞超微结构的损伤。
The experimental results showed that Salvia miltiorrhiza can obviously inhibit the normal and damaged lipid peroxidation of hepatocytes, induce the synthesis of cytochrome P450, prevent the decrease of injured hepatocyte proteins, DNA, RNA, urea and ceruloplasmin, and reduce the hepatotoxicity on in vitro culture. Ultrastructure damage of liver cells.