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N,N-二取代的磺酰胺与氯三甲基硅烷和碘化钠各 1.5摩尔当量 (生成碘三甲基硅烷 )在乙腈中中性条件下回流反应 ,脱去保护基得到仲胺 ,12例收率 70 %～ 88%磺酰胺用碘三甲基硅烷脱去磺酰基@马翔
1.5 molar equivalents of each of N, N-disubstituted sulfonamide and chlorotrimethylsilane and sodium iodide (iodotrimethylsilane) is refluxed under neutral conditions in acetonitrile to remove the protective group to give secondary amine, 12 Example yield 70% ~ 88% sulfonamide with iodine trimethylsilane off sulfonyl @ Ma Xiang