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目的分析儿童手足口病的临床治疗方法。方法选取2010年4月—2012年4月我院收治的手足口病患儿150例,将其随机分为治疗组(78例)和对照组(72例)。对照组给予常规药物治疗,治疗组在常规治疗基础上肌肉注射干扰素,观察并比较两组患儿平均退热时间、平均手足部皮疹消退时间、平均口腔溃疡消退时间和治疗效果。结果治疗组平均退热时间、平均手足部皮疹消退时间、平均口腔溃疡消退时间和平均住院时间均短于对照组(P<0.05)。对照组总有效率为73.6%(53/72),低于治疗组的96.2%(75/78)(P<0.05)。两组患儿均无不良反应发生。结论干扰素联合常规治疗可以有效提高手足口病治疗效果,促进患儿康复,且安全。
Objective To analyze the clinical treatment of hand, foot and mouth disease in children. Methods 150 cases of HFMD in our hospital from April 2010 to April 2012 were randomly divided into treatment group (78 cases) and control group (72 cases). The control group was given conventional drug therapy. The treatment group was intramuscularly injected with interferon on the basis of routine treatment. The average antipyretic time, the average subcutaneous rash subsided time, the average oral ulcer subsided time and the therapeutic effect were observed and compared between the two groups. Results The average duration of fever, average subcutaneous rash time, average oral ulcer subsidence and average length of hospital stay in the treatment group were shorter than those in the control group (P <0.05). The total effective rate in the control group was 73.6% (53/72), which was lower than 96.2% (75/78) in the treatment group (P <0.05). No adverse reactions occurred in both groups of children. Conclusion Interferon combined with conventional treatment can effectively improve the treatment effect of hand, foot and mouth disease and promote the recovery of children and safety.