家兔血浆性激素对电针抑制内毒素发热效应的影响

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用内毒素(ET)复制家兔发热模型,将动物分为电针组和对照组,按性别分别统计处理实验结果,雌兔电针组体温上升受到明显抑制,比较两组动物的发热高峰(ΔT)及体温反应指数(TRI)其差异性均显著。雄兔电针组的AT和TRI均低于对照组,但其差异性不显著。给雄性家兔去势,去势后1个月、3个月分别用ET复制发热模型,去势后1个月比较电针组及对照组动物的ΔT其差异性显著,而TRI去势后3个月差异显著。去势后1个月血浆雌二醇水平较去势前有明显增加。而血浆睾酮水平去势后3个月明显减少。表明针刺抑制ET发热效应和血浆性激素水平有关。 Endogenous toxin (ET) was used to replicate the rabbit febrile animal model. The animals were divided into EA group and control group. The results of the experiment were statistically processed according to gender. The increase in body temperature of the female EA group was significantly inhibited. The fever peak of the two groups of animals was compared ( ΔT) and body temperature response index (TRI) were significantly different. Compared with the control group, the AT and TRI of male rabbit electroacupuncture group were lower than the control group, but the difference was not significant. The male rabbits were castrated and the febrile models were replicated with ET 1 month and 3 months after castration respectively. The difference in ΔT between the electroacupuncture group and the control group was significant one month after castration. After TRI castration, the difference was significant. The difference was significant at 3 months. The level of plasma estradiol after castration was significantly higher than that before castration. The plasma testosterone level decreased markedly after 3 months of castration. It is shown that acupuncture inhibits ET fever and plasma sex hormone levels.
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