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目的通过相干光断层成像(optical coherence tomography,OCT)观察原发性视网膜色素变性(retinitis pigmentosa,RP)患者的视网膜黄斑区图像特征。方法对临床诊断为原发性视网膜色素变性的25例50只眼进行相干光断层成像检查,观察形态特点并进行厚度测量。结果原发性视网膜色素变性患者黄斑区的相干光断层图像,通常有6种表现:1.神经上皮层弥漫性增厚即水肿(厚度>170μm),13只眼(26%)。2.黄斑囊样水肿8只眼(16.7%)。3.神经上皮层萎缩薄变(<120μm),18只眼(36%)。4.视网膜色素上皮层和脉络膜毛细血管层萎缩薄变,见于所有患者。5.黄斑前膜4只眼(8%)。6.黄斑正常厚度。结论相干光断层成像有助于较早地发现RP的各种黄斑病变,是很有用的检查方法。
Objective To observe the macular image features in patients with primary retinitis pigmentosa (RP) by optical coherence tomography (OCT). Methods Fifty-five eyes (25 eyes) diagnosed as primary retinitis pigmentosa were examined by coherence tomography. Morphological characteristics were observed and thickness measurements were performed. Results There were six kinds of coherent photocoagulation images of macula in patients with primary retinitis pigmentosa: diffuse thickening of the neuroepithelium (edema> 170μm) and 13 eyes (26%). Macular cystoid edema in 8 eyes (16.7%). 3. Nerve epithelial atrophy thinning (<120μm), 18 eyes (36%). 4. Retinal pigment epithelium and choriocapillaris atrophy thin, found in all patients. 5 pre-macular membrane in 4 eyes (8%). 6. Normal macular thickness. Conclusion Coherent light tomography is helpful to find all kinds of macular degeneration of RP earlier and is a useful method for the examination.