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本文根据患者接触史、临床诊断和肺组织是否找到“石棉小体”三个指标,选择3例石棉肺待查、1例石棉肺Ⅰ期(AⅠ)的患者支气管活检样品进行了电镜超微结构观察和矿物元素成份分析,发现其超微结构病理学特点是肺组织的弥漫性纤维病变和肺上支的瘤样增生、鳞化和问变,以及巨噬细胞吞噬了较多的纤维状或针状颗粒,完全符合石棉肺的形态特征。细胞吞噬的异物经能谱(DEAX)分析,出现Si和Mg峰,证明患者吸入的异物是石棉纤维并属温石棉。
According to the patient’s contact history, clinical diagnosis and lung tissue whether to find “asbestos body” three indicators, select three cases of asbestosis, one case of ascites lung Ⅰ stage (AⅠ) in patients with bronchial biopsy samples under electron microscopy Observation and analysis of mineral elements and found that its ultrastructural pathology is characterized by pulmonary fibrosis and pulmonary lung tumor-like hyperplasia, scaling and asked change, and macrophages phagocytosed more fibrous or Acicular particles, in full compliance with the morphological characteristics of asbestos lung. Foreign body phagocytosis was analyzed by energy dispersive spectroscopy (DEAX), showing peaks of Si and Mg, indicating that the aspirated foreign body was asbestos fibers and chrysotile.