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目的探讨全凭七氟醚吸入麻醉在小儿全麻醉诱导中的应用效果。方法选取我院收治的择期行全麻手术治疗的180例患儿作为研究对象,将其随机均分为两组。观察组行全凭七氟醚吸入麻醉,对照组行氯胺酮静脉麻醉,比较两组麻醉效果及不良反应。结果观察组麻醉诱导时间、自主呼吸恢复时间、苏醒时间分别为(1.14±0.45)min、(6.04±0.52)min、(12.64±5.67)min,均显著短于对照组,差异有统计学意义(P<0.01);观察组肢体活动、恶心呕吐、分泌物增加、一过性呼吸抑制、术后躁动发生率分别为2.22%、6.67%、1.11%、0、1.11%,均显著低于对照组,差异有统计学意义(P<0.01)。结论全凭七氟醚吸入麻醉应用于小儿全麻手术中诱导迅速,苏醒快,不良反应少,安全性高,值得临床推广应用。
Objective To investigate the effect of inhalation anesthesia on induction of total anesthesia in children. Methods A total of 180 children undergoing general anesthesia surgery in our hospital were selected as the study subjects and randomly divided into two groups. The observation group was anesthetized with sevoflurane inhalation anesthesia, and the control group received ketamine intravenous anesthesia. The anesthetic effects and adverse reactions in both groups were compared. Results The induction time of spontaneous breathing, recovery time of spontaneous breathing and recovery time in observation group were (1.14 ± 0.45) min, (6.04 ± 0.52) min and (12.64 ± 5.67) min, respectively, which were significantly shorter than those in control group P <0.01). The limb movement, nausea and vomiting, increased secretions, transient respiratory depression and postoperative agitation in observation group were 2.22%, 6.67%, 1.11% and 0.11% respectively, which were significantly lower than those in control group , The difference was statistically significant (P <0.01). Conclusions All the sevoflurane inhalation anesthesia applied to pediatric general anesthesia in the induction of rapid, rapid recovery, less adverse reactions, high safety, worthy of clinical application.