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胃癌严重地危害我国劳动人民的健康,为了研究其根治的办法,建立胃癌模型非常必要。本实验企图在较短的时间内在小鼠诱发与人体胃癌类似的腺胃癌瘤。材料和方法第一批实验采用体重20克左右的小白鼠21只,第二批实验采用体重18～22克雄性小白鼠82只,无菌手术在腺胃粘膜面穿挂含甲基胆蒽线结。首先打开腹腔取出胃,在腺胃前壁作一长约2毫米的切口,然后将缝针自切口进入胃腔,从幽门小弯侧粘膜面经肌层和浆膜穿出,在浆膜表面打结固定,使含甲基胆蒽线结紧贴于粘膜。顺序分别将腺
Stomach cancer seriously endanger the health of our working people, in order to study its cure, it is necessary to establish a gastric cancer model. This experiment attempts to induce similar gastric adenocarcinoma of the human stomach in mice in a short period of time. MATERIALS AND METHODS The first experiments used 21 mice weighing 20 g and the second experiment used 82 male mice weighing 18-22 g. Aseptic surgery was performed on the glandular gastric mucosa with methylcholane line Knot First open the abdominal cavity to take out the stomach, make an incision of about 2 mm in front of the glandular stomach, and then the needle into the stomach cavity from the incision, from the small pyloric side of the pyloric mucosa through the myometrial and serosal penetration in the serosal surface Tie knot fixed, so that containing methyl choleranthin line knot attached to the mucosa. The order will be gland