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目的观察质子泵抑制剂泮托拉唑治疗透析消化道出血患者的临床效果。方法 76例透析消化道出血患者,通过抽签法随机分为B1组和B2组,各38例。B1组临床选择泮托拉唑进行治疗;B2组临床选择法莫替丁进行治疗。比较两组患者的治疗总有效率。结果 B1组治疗总有效率为97.37%,高于B2组的76.32%,差异有统计学意义(P<0.05)。结论对透析消化道出血患者,临床选择质子泵抑制剂泮托拉唑进行治疗,能够获得显著疗效,提高透析消化道出血患者的生活质量。
Objective To observe the clinical effect of proton pump inhibitor pantoprazole in dialysis patients with gastrointestinal hemorrhage. Methods 76 cases of dialysis patients with gastrointestinal bleeding were randomly divided into B1 and B2 groups by lottery method, each 38 cases. Group B1 was treated with pantoprazole; Group B2 was treated with famotidine. The total effective rate was compared between the two groups. Results The total effective rate in group B1 was 97.37%, which was higher than that in group B2 (76.32%), the difference was statistically significant (P <0.05). Conclusion The treatment of pantoprazole, a proton pump inhibitor, in dialysis patients with gastrointestinal hemorrhage can obtain significant curative effect and improve the quality of life of dialysis patients with gastrointestinal bleeding.