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目的分析口腔颌面部多间隙感染的临床表现及病原菌分布,以期指导临床治疗。方法回顾性分析2008年1月至2012年10月青岛大学医学院附属医院收治的46例口腔颌面多间隙感染患者的临床资料,分析其感染来源、病原菌种类及治疗方法。结果共培养出病原菌50株,革兰阳性球菌、革兰阴性杆菌、革兰阳性杆菌及白色念珠菌分别占84%、12%、2%、2%,其中前5位病原菌分别是金黄色葡萄球菌、星座链球菌星座亚种、F群链球菌、表皮葡萄球菌及肺炎克雷伯菌肺炎亚种。结论口腔颌面部多间隙感染多为混合感染,合理使用抗生素、及时切开引流是早期控制多间隙感染的有效手段。
Objective To analyze the clinical manifestations and pathogens distribution of oral and maxillofacial multiple space infections in order to guide the clinical treatment. Methods The clinical data of 46 patients with multiple oral or maxillofacial infections admitted to the Affiliated Hospital of Medical College of Qingdao University from January 2008 to October 2012 were retrospectively analyzed. The sources of infection, types of pathogens and treatment methods were analyzed. Results A total of 50 strains of pathogens were cultured. Gram-positive cocci, Gram-negative bacilli, Gram-positive bacilli and Candida albicans accounted for 84%, 12%, 2% and 2% respectively. The top five pathogenic bacteria were golden yellow grape Cocci, Streptococcus constellatus subsp. Constellation, F group Streptococcus, Staphylococcus epidermidis and Klebsiella pneumoniae pneumonia. Conclusion Most of the infections in oral and maxillofacial regions are mixed infection. Rational use of antibiotics and timely dissection and drainage are effective methods to control multiple interstitial infections in the early stage.