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固本消敏汤是老中医治疗过敏疾病的经验方,主要药物有黄芪、防风、苦参、五味子、炙草等。以此方为基础方,用于治疗临床多种过敏性疾病.动物实验已证实该方对导致PCA反应的特异性IgE有明显的抑制作用。但对其它免疫细胞的作用尚不了解。本研究的目的在于:(1)研究固本消敏汤对各类淋巴细胞的影响,从而初步了解该方的作用机制; (2)通过对淋巴细胞增殖功能的检测,分析各主要药物在复方中的作用,了解其中某些药之间可能存在的交互作用。
Guben Xiaomin Decoction is the experience of old Chinese medicine in the treatment of allergic diseases. The main medicines are Huangqi, wind-proof, Sophora flavescens, Schisandra chinensis, Echinochloa crusgalli, and so on. This side is used as a basis for the treatment of a variety of clinical allergic diseases. Animal experiments have confirmed that this side has a significant inhibitory effect on the specific IgE that causes PCA response. However, the effects on other immune cells are still unknown. The purpose of this study is to: (1) study the effect of Guben Xiaomin Decoction on various types of lymphocytes, so as to understand the mechanism of action of this side; (2) analyze the major drugs in the compound through the detection of lymphocyte proliferation Role in understanding the possible interactions between certain drugs.