压电基因传感器是近年发展起来的一种新的基因检测手段。同以往的标记检测法相比具有很多的优越性 :不需要标记 ,操作简单 ,费时较少 ,在液相状态下便可直接获取杂交信息 ,可以对杂交反应进行动态、定量地监测。本文就压电基因传感器的原理、应用研究情况及发展趋势进行了综述 Piezoelectric gene sensor is a new genetic testing method developed in recent years. Compared with the traditional method of labeling detection, it has a lot of advantages: no need of marking, simple operation and less time-consuming. The hybridization information can be directly obtained in the liquid phase, and the hybridization reaction can be monitored dynamically and quantitatively. In this paper, the principle, applied research situation and development trend of piezoelectric gene sensor are reviewed.