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为研究珠子草对乙肝病毒标志物的作用，本文用湛江、深圳、海南产的珠子草进行对ＨＢｓＡｇ抑制作用的体外和临床试验。珠子草制成浸液，在３７℃下与等量ＨＢｓＡｇ阳性人血清混合作用不同时间（３、２４、４８小时）后，用ＲＩＡ检测ＨＢｓＡｇ滴度的变化，作用４８小时ＨＢｓＡｇ滴度下降２５％左右，提示珠子草在体外试验对ＨＢ－ｓＡｇ具有一定的抑制能力。２０例ＨＢｓＡｇ阳性患者口服珠子草全草干粉５００ｍｇ／次，每日服３次，共治疗３月，治后仅１例ＨＢｓＡｇ阴转（５％），ＨＢｅＡｇ阳性８例、前Ｓ２阳性６例皆未见阴转，半年后随访结果与治疗结束时相仿，总疗效不满意。
In order to study the effect of Beadgrass on hepatitis B virus markers, in vitro and in vivo experiments on the inhibition of HBsAg by Beadgrass produced in Zhanjiang, Shenzhen and Hainan were carried out. Beadgrass made immersion, HBsAg-positive human serum mixed with the same amount of different time (3,24,48 hours) at 37 ℃, RIA detection of HBsAg titer changes, the effect of 48 hours HBsAg titers decreased by 25% Or so, suggesting that Bead grass in vitro test on HB-sAg has a certain inhibitory capacity. Twenty HBsAg positive patients were orally administrated with 500 mg of Beadgrass dry grass powder three times a day for 3 months. Only one case of HBsAg negative conversion (5%), HBeAg positive in 8 cases and pre S2 positive cases No overcast, six months after follow-up results and the end of treatment similar, the total effect is not satisfied.