论文部分内容阅读
探讨老年心肌梗塞(MI)与脂蛋白(a)[Lp(a)]、血小板活性及凝血功能的关系。方法:选择经冠状动脉造影(CAG)诊断为老年MI患者(n=68)作为老年MI组,选择以胸闷和胸痛等不典型症状来诊、但CAG正常的患者(n=74)作为对照组;同时采集静脉血检测Lp(a)、血小板a颗粒膜蛋白-140(GMP-140)、血浆纤维蛋白原(FG)、血浆纤维蛋白肽A(FPA)、血脂、血糖(FGB)和血小板(Plt)。结果:与对照组比较,老年MI患者LP(a)、GMP-140、FG和FPA均增高(P>0.05);总胆固醇(TC)与低密度脂蛋白(LDL-C)增高(P>0.05);甘油三酯(TG)、高密度脂蛋白(HDL)、FGB及Plt差异无显著性(P>0.05)。结论:老年MI患者与LP(a)、GMP-140、FG和FPA的增高关系密切,TC及LDL-C的增高与老年MI有关。
To investigate the relationship between senile myocardial infarction (MI) and lipoprotein (a) [Lp (a)], platelet activity and coagulation function. Methods: Elderly MI patients (n = 68) diagnosed as coronary artery disease by coronary angiography (CAG) were selected as the elderly MI group. The patients with atypical symptoms such as chest pain and chest pain were selected for diagnosis. Patients with normal CAG (n = 74) Blood samples were collected for detection of Lp (a), GMP-140, FG, FPA, FGB and platelet Plt). Results: Compared with the control group, LP (a), GMP-140, FG and FPA were significantly increased in elderly patients with MI (P> 0.05), total cholesterol (TC) and low density lipoprotein ); TG, HDL, FGB and Plt showed no significant difference (P> 0.05). Conclusion: Elderly patients with MI are closely related to the increase of LP (a), GMP-140, FG and FPA, and the increase of TC and LDL-C are related to the elderly MI.