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目的探讨糖化血红蛋白(HbAIc)在糖尿病诊断以及治疗中的临床价值。方法选择98例确诊为糖尿病的受检者以及120例健康人群禁食10～12 h,测定空腹血糖(FPG)、餐后2 h血糖(2hPG)及测定糖化血红蛋白(HbAIc)。结果糖尿病组的血糖及糖化血红蛋白均明显高于正常对照组(P<0.01);糖尿病并发症的发生率随HbAIc水平升高而升高(P<0.01)。结论 HbA1c与FPG、2hPG联合监测作为筛选诊断DM并指导治疗较好适合的方法且简单、便捷、可重复性好的敏感指标。
Objective To investigate the clinical value of glycosylated hemoglobin (HbAIc) in the diagnosis and treatment of diabetes mellitus. Methods Ninety patients diagnosed with diabetes mellitus and 120 healthy subjects were fasted for 10-12 h. FPG, 2hPG and HbAIc were measured. Results The blood glucose and glycosylated hemoglobin in diabetic group were significantly higher than those in normal control group (P <0.01). The incidence of diabetic complications increased with the increase of HbAIc level (P <0.01). Conclusion Combined monitoring of HbA1c with FPG and 2hPG is a sensitive, simple, convenient and reproducible method for screening DM and guiding the treatment of patients with moderate to severe symptoms.