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目的 探讨原发性骨恶性淋巴瘤 (PLB)的临床病理特征及治疗。方法 对 11例PLB进行回顾性分析。结果 单纯截肢 3例 ,肿瘤扩大切除加放疗 1例 ,截肢加化疗 1例 ,单纯化疗 2例 ,化疗加放疗 1例 ,活检后未治 3例 ;半年内死亡 2例 ,1年内死亡 1例 ,2年内死亡 2例。随访中仍存活 4例 ,其中 6个月 1例 ,1年 1例 ,2年 1例 ,4年 1例 ;失访2例。结论 PLB临床资料无特异性 ,诊断及分型主要依据病检及免疫组化结果 ,治疗以放疗及化疗为主
Objective To investigate the clinicopathological features and treatment of primary malignant lymphoma of bone (PLB). Methods 11 cases of PLB were retrospectively analyzed. Results There were 3 cases of simple amputation, 1 case of tumor enlargement and excision plus radiotherapy, 1 case of amputation and chemotherapy, 2 cases of simple chemotherapy, 1 case of chemotherapy and radiotherapy, 3 cases of untreated biopsy, 2 cases of death within 1 year and 1 case of death within 1 year, Two cases died in 2 years. In the follow-up, 4 patients survived, including 6 cases in 1 case, 1 case in 1 year, 1 case in 2 years and 1 case in 4 years. There were 2 cases lost to follow-up. Conclusion The clinical data of PLB is non-specific. The diagnosis and classification are mainly based on the results of pathological examination and immunohistochemistry. The treatment is mainly radiotherapy and chemotherapy