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目的 比较甲状腺切除手术中应用钳式超声刀和传统电刀的效果.方法 前瞻性收集笔者所在医院于2016年2月至2017年1月期间收治的160例接受开放性甲状腺手术患者的临床资料,随机分为钳式电刀组和传统电刀组,各80例.比较2组患者的手术效果指标、术后并发症发生情况和术后切口数字疼痛分级法(NRS)评分.结果 在手术效果指标方面,钳式超声刀组患者的手术时间、术中出血量、术后引流量、术后引流时间、手术切口长度和住院时间均短于或低于传统电刀组,差异均有统计学意义(P＜0.05);在术后并发症方面,钳式超声刀组患者的声音嘶哑、伤口出血和甲状旁腺功能减退发生率,以及总并发症发生率均低于传统电刀组(P＜0.05),但2组患者的低钙血症、伤口感染和暂时性喉返神经麻痹发生率比较差异均无统计学意义(P＞0.05);在术后切口NRS评分方面,重复测量资料的方差分析结果表明,各时点钳式超声刀组患者的NRS评分均低于传统电刀组(P＜0.05).结论 开放性甲状腺手术中使用钳式超声刀可有效提高手术效果,减轻术后的疼痛,降低并发症的发生率.“,”Objective To compare the efficacy and complication between harmonic scalpel and traditional electric knife in open thyroidectomy.Methods A total of 160 thyroid disease patients who underwent open thyroidectomy in The Fifth Affiliated Hospital of Southern Medical University from February 2016 to January 2017,were collected and divided into harmonic scalpel group and traditional electric knife group randomly,each group enrolled 80 patients.The efficacy of thyroidectomy,postoperative pain,and complication between the 2 groups were compared and analyzed.Results Compared with the traditional electric knife group,the operation time,intraoperative blood loss,postoperative drainage volume,postoperative drainage time,length of incision,and hospital stay were all significantly lower in the harmonic scalpel group (P＜0.05).The incidences hoarseness,wound bleeding,hypoparathyroidism,and total complication in the harmonic scalpel group were all lower than those of the traditional electric knife group (P＜0.05).The pain scores after operation in the harmonic scalpel group were significant lower than corresponding pain scores of the traditional electric knife group (P＜0.05).Conclusion The harmonic scalpel could effectively improve the efficacy of open thyroidectomy,reduce the pain degree and the incidence of complication in thyroid disease patients.