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作者从455例经电镜检查的急性白血病中选出诊断8例急性嗜碱粒细胞白血病(男5例女3例,年龄9～82岁)。他们的临床表现与其它AML 不能区别,7例经化疗,4例取得CR。存活1～63~+月。实验参数:WBC(2.8～144)×10~9/L,Hb 53～134g/L(7例贫血),8例血小板计数均减少。骨髓标本原始细胞占33～99%,血液和骨髓嗜碱粒细胞增多者各3例,8例中无一见到Auer 氏小体。光镜检查,2例原始细胞中偶见明显的嗜碱颗粒,伴有细胞向成熟嗜碱粒细胞和肥大细胞分化。此2例血和骨髓中也有成熟和幼稚的嗜碱粒细胞增多。3例原始细胞无颗粒,且不存在嗜碱粒细胞分化证据;另3例在原始细胞中罕见或偶见嗜天青或深蓝色颗粒,其中有些颗
The authors selected 8 cases of acute basilitic leukemia (3 males and 5 females, aged 9-82 years) from 455 acute leukemias diagnosed by electron microscopy. Their clinical manifestations and other AML can not be distinguished, 7 cases of chemotherapy, 4 cases of CR. Survival of 1 ~ 63 ~ + month. Experimental parameters: WBC (2.8 ~ 144) × 10 ~ 9 / L, Hb 53 ~ 134g / L (7 anemia), 8 cases of platelet count were reduced. Bone marrow specimens of primitive cells accounted for 33 to 99%, blood and bone marrow basophils increased in 3 cases, no one of 8 cases to see Auer’s body. Light microscopy, occasionally seen in 2 cases of primitive cells basophilic granules, accompanied by cells to mature basophils and mast cells. The two cases of blood and bone marrow also have mature and naive basophils increased. 3 cases of primitive cells without particles, and there is no evidence of basophil differentiation; the other 3 cases rare or occasional indulgent cyanid or dark blue particles in the primitive cells, some of which