目前研究的结果提示骨髓基质细胞对于调节造血干细胞的增殖与分化有重要作用。由骨髓培养生长的纤维母细胞可反映基质细胞的一个结构成分。这种纤维母细胞对造血的调节是复杂的,它不仅可释放一种,可溶性因子,使小鼠造血干细胞(S—CFu)或人类造血祖细胞(GM—CFu)在体外的存活延长,且其形成的集落也刺激粒系祖细 The results of the present study suggest that bone marrow stromal cells play an important role in the regulation of the proliferation and differentiation of hematopoietic stem cells. Fibroblasts grown from bone marrow cultures can reflect a structural component of stromal cells. This hematopoietic regulation of fibroblasts is complicated by not only releasing a soluble factor that prolongs in vitro survival of mouse hematopoietic stem cells (S-CFu) or human hematopoietic progenitor cells (GM-CFu), and The formation of colonies also stimulate granulocyte progenitor