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采用染色体ｃｄ带技术对１７例肺癌患者和１０例肺部良性病变患者外周血细胞染色体ｃｄ结构丢失作了初步分析，结果发现肺癌患者ｃｄ结构丢失频率显著高于肺部良性病变患者和正常人对照组（Ｐ＜０．０１），而肺部良性病变组和正常人对照组之间无显著差异（Ｐ＞０．０５）。本研究结果提示肺场患者外周血细胞染色体ｃｄ结构丢失有增高的趋势。本文对ｃｄ结构丢失与癌患病人细胞非整倍性畸变的关系进行了讨论。
The chromosomal cd band technique was used to analyze the loss of chromosomal cd structure in peripheral blood cells in 17 patients with lung cancer and 10 patients with benign lung disease. The results showed that the frequency of cd structural loss in lung cancer patients was significantly higher than that in patients with benign lung disease and normal controls. (P<0.01), but there was no significant difference between the benign lung disease group and the normal control group (P>0.05). The results of this study suggest that the loss of chromosomal cd structure in peripheral blood cells of patients with lung field has an increasing trend. This article discusses the relationship between loss of cd structure and aneuploidy aberration in patients with cancer.