目的：探讨角膜接触镜应用于翼状胬肉切除术的有效性及安全性。方法选取我科2013年1月～2014年6月在我院眼科就诊接受翼状胬肉切除联合带蒂结膜瓣转位移植术的患者100例（128眼），其中28例为双眼，随机分为2组：角膜接触镜组和对照组，每组50例（64眼）。角膜接触镜组在手术结束时角结膜表面配戴绷带型角膜接触镜，术后3d取下绷带型角膜接触镜，对照组术后当天包扎术眼，两组术后均给予抗生素滴眼液和促进角膜创面修复眼药水点眼，观察术后患者角膜创面恢复情况及眼部刺激症状。比较术后2h、6h、24h、48h、72h2组患者疼痛程度、术后3d角膜上皮荧光素染色评分及角膜上皮缺损面积的差异，并观察并发症的发生情况。结果观察组患者疼痛程度评分均较对照组显著降低（均为P＜0.01）；术后3d角膜上皮荧光素染色评分对照组与观察组之间差异无统计学意义（P=0.135）；观察组患者角膜上皮缺损面积、角膜上皮愈合时间等指标与对照组比较差异有统计学意义（P=0.041）；随诊2～6个月，观察组术后复发率4%，对照组术后复发率为10%，两组患者复发率比较差异有统计学意义（X2=4.392，P<0.05）；两组均未见感染、移植片愈合不良、结膜下囊肿等并发症发生。结论角膜接触镜能加速翼状胬肉术后角膜创面的修复，减轻翼状胬肉切除术后疼痛反应，促进角膜上皮愈合，并能提高医务人员工作效率，值得临床医师推广应用。“,”Objective: To evaluate the efficacy and safety of application of corneal contact lens in pterygium excision. Methods: select the Department in 2013 January to 2014 June in our hospital 100 cases admitted to Department of Ophthalmology received pterygium excision combined with conjunctival flap transposition grafting patients (128 eyes), including 28 cases of eyes, were randomly divided into 2 groups: corneal contact lens group and control group, each group of 50 cases (64 eyes). Corneal contact lens group at the end of the operation ocular surface wear a bandage contact lens, postoperative 3D removed the bandage contact lens, control group on postoperative day bandaging the eye, two groups of patients were treated with antibiotic eye drops and promote corneal wound repair eye drops, observation of postoperative patients with corneal wound healing and eye irritation. Comparison of postoperative 2h, 6h, 24h, 48h, 72h2 groups of patients with postoperative pain degree, 3D corneal epithelium fluorescein staining of corneal epithelial defect area difference score and the occurrence of complications, and observe. Results: the patients pain score were significantly lower than the control group (P<0.01); postoperative 3D corneal epithelium fluorescein staining score differences between the control group and the observation group had no statistical significance (P=0.135); there was significant difference between the patients in the observation group corneal epithelial defect area, corneal epithelial healing time and other index the control group (P=0.041); folowed up for 2~6 months, 4% patients in the observation group the recurrence rate after surgery in the control group, the recurrence rate was 10%, the rate of recurrence in patients with comparison of difference between the two groups was statisticaly significant (X2=4.392, P<0.05); the two groups had no infection, graft healing adverse, conjunctival cyst complications. Conclusion: corneal contact lens can accelerate corneal wound repair after excision of pterygium after pterygium excision, aleviate pain reaction, promote healing of corneal epithelium, and can improve the work efficiency of the medical staff, and is worthy of popularization and application of clinicians.