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为比较阿朴吗啡舌下给药与口服枸橼酸西地那非治疗男性勃起功能障碍(ED)的疗效和安全性,Pavone C等进行了一项随机、交叉对比的前瞻性研究。共有62例不同病因和严重程度的异性恋ED患者纳入随机分组,但仅有34例患者可供评价有效性和耐受性。研究步骤依次为2~4周的试验期、4周治疗期、4周清除期、4周的替换疗法作为附加治疗期。两种治疗秩序由密封于口袋中的随机
To compare the efficacy and safety of apomorphine sublingual and oral administration of sildenafil citrate in the treatment of male erectile dysfunction (ED), a randomized, cross-prospective, prospective study was conducted by Pavone C et al. A total of 62 patients with heterosexual ED of different etiologies and severity were included in the randomized study but only 34 patients were evaluated for efficacy and tolerability. The research steps were followed by 2 to 4 weeks of trial, 4 weeks of treatment, 4 weeks of clearance, 4 weeks of replacement therapy as an additional treatment period. Both treatment orders are sealed by randomization in the pocket