Advances in stents design have led to a substantial increase in the use of stents for a variety of digestive diseases. Initially developed as a non-surgical treatment for palliation of esophageal cancer, the stents now have an emerging role in the management of malignant and benign conditions as well as in all segments of the gastrointestinal tract. In this review, relevant literature search and expert opinions have been used to evaluate the key-role of stenting in gastrointestinal benign and malignant diseases. Advances in stents design have led to a substantial increase in the use of stents for a variety of digestive diseases. conditions as well as in all segments of the gastrointestinal tract. In this review, relevant literature search and learned opinions and scientists opinions have been been used to evaluate the key-role of stenting in gastrointestinal benign and malignant diseases.