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以尿蛋白、尿管型、尿红细胞、血清 Cr、BUN、双肾病理活检的 GD、GC、GP、GM 共九项客观指标,采用抗原抗体复合物免疫学方法诱发成年健康家兔形成实验性肾炎的疾病模型。并按照中医气血立论,组成肾康(黄芪、当归等)、肾通(大黄、红花等)和康通(两组药物合用)三组中药配方,分别治疗家兔实验性肾炎,外设环强组(环磷酰胺+强的松)、康强组(肾康组药物+强的松)、空白组比较观察其药效。结果九项客观指标同步地反映药效大小顺序是:康通≥肾通≥肾康>康强≥环强>空白,且具有统计学意义,证明气血立论治疗实验性肾炎具有一定意义.
Urine protein, urinary tube type, urinary tract type, urinary erythrocyte, serum Cr, BUN, and GD, GC, GP, and GM of two kidney biopsy specimens were used to test the adult healthy rabbits induced by antigen-antibody complex immunoassay. Nephritis disease model. According to the theory of blood and blood of TCM, three groups of traditional Chinese medicine formulas consisting of Shenkang (Huangxi, Chinese angelica, etc.), Kidney Tong (rhubarb, safflower, etc.) and Kangtong (the combination of the two groups of drugs) are used to treat experimental nephritis in rabbits and peripherals. The efficacy was observed in the ring-strength group (cyclophosphamide + prednisone), Kangqiang group (Kangkang group + prednisone), and blank group. Results Nine objective indicators synchronously reflect the order of drug efficacy: Kang Tong ≥ Shen Tong ≥ Shen Kang> Kang Qiang ≥ ring strength> blank, and it has statistical significance, which proves that qi and blood prescriptions have certain significance for the treatment of experimental nephritis.