【摘 要】
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Dear Editor,What is the molecular basis of memory formation? Many genes have been implicated in this process,including those involved in neural cell adhesion,mR
【机 构】
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McGovern Institute for Brain Research, Ministry of Education Key Laboratory of Protein Sciences, Tsi
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Dear Editor,What is the molecular basis of memory formation? Many genes have been implicated in this process,including those involved in neural cell adhesion,mRNA transport,translation control,and cAMP-PKA signaling.Drosophila,with easy accessibility to genetic,molecular,and behavioral analyses,was also employed in olfactory leaing studies and many key genes underlying memory formation were identified in these studies (Bellen et al.,2010).The majority of identified genes have been shown to be intensively expressed in the mushroom body (MB) of the Drosophila brain (Davis,2005),including rut (adenylyl cyclase),DCO (the catalytic subunit of PKA),and AKAP Yu (Heisenberg,2003;Davis,2005;Lu et al.,2007).However,these genes are far from enough to understand memory formation comprehensively.
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