癫痫是一种常见的神经系统疾病，抗癫痫药物是治疗癫痫的主要手段。然而，对于癫痫患者的撤药时机目前尚无定论。近年来一些大型前瞻性研究对癫痫患者撤药进行了评估和分析，提出一些指导意见。文中着重谈谈影响癫痫患者撤药预后的因素以及对撤药时机的选择，希望能提高对癫痫患者撤药的认识，指导临床实践。“,”Epilepsy is the common neurological disease, and antiepileptic drugs are the main means for the treatment of epilepsy. However, there is no conclusion on the timing of drug withdrawal in patients with epilepsy. In recent years, some large-scale prospective studies have provided some guidance on anti-epileptic drugs withdrawal. This article focused on the factors affecting the prognosis and timing of drug withdrawal, hoping to further the understanding of anti-epileptic drugs withdrawal and instruct clinical practise.