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持续呼吸道正压(CPAP)是用于新生儿呼吸系统疾病的重要支持技术之一,近30年来,尤其是近10余年来人们对于CPAP的应用模式、作用和副作用及其与肺泡表面活性物质的应用关系等方面都进行了比较系统的研究,结果显示,CPAP在新生儿呼吸系统疾病中的支持作用是肯定的,并且其与肺表面活性物质的联合使用可以降低机械通气的应用,并且现在对于CPAP对肺组织影响的研究已经进入分子水平,但是目前对于CPAP的远期影响尚缺乏系统性的研究。
Continuous positive airway pressure (CPAP) is one of the important supportive technologies for neonatal respiratory diseases. In recent 30 years, especially for the past 10 years, the application mode, effect and side effect of CPAP and its relationship with alveolar surfactant Application relationships and other aspects of a more systematic study, the results show that CPAP in neonatal respiratory disease supportive role is affirmative, and its combination with pulmonary surfactant can reduce the application of mechanical ventilation, and now for The impact of CPAP on lung tissue has entered the molecular level, but the current impact on the long-term impact of CPAP is still lack of systematic research.