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目的:探讨早产胎膜早破应用不同方法治疗对母婴结局的影响。方法:于2015年5月至2016年10月收集肇庆市第一人民医院早产胎膜早破患者进行研究,共有患者50例,随机分为观察组与对照组,两组均给予保胎治疗,观察组在保胎治疗的基础上,给予娩出后早产儿抗感染处理。比较两组患者不同孕周的母婴结局,包括剖宫产、宫内感染、新生儿窒息率、新生儿死亡。结果:在28~34周内,观察组母婴不良结局的发生率明显低于对照组,差异具有统计学意义(P<0.05);在34~36周内,观察组母婴不良结局的发生率明显低于对照组,差异具有统计学意义(P<0.05);在36~37周内,两组母婴不良结局的发生率比较,差异均无统计学意义(P>0.05)。结论:针对不同早产胎膜早破情况应该根据不同孕周、患者的实际情况采取相应的保胎治疗方法,以最大程度地保证母婴安全,娩出后早产儿应及时给予针对性的抗感染处理措施,改善新生儿结局。
Objective: To investigate the effect of different methods of preterm premature rupture of membranes on maternal and infant outcomes. Methods: From May 2015 to October 2016, we collected the patients with premature rupture of membranes in Zhaoqing First People’s Hospital. A total of 50 patients were randomly divided into observation group and control group. Both groups were given tocolytic treatment, Observation group on the basis of miscarriage treatment, giving anti-infective treatment of premature infants after delivery. Maternal and infant outcomes at different gestational weeks in both groups were compared, including cesarean section, intrauterine infection, neonatal asphyxia and neonatal death. Results: The incidence of maternal and child adverse outcomes in the observation group was significantly lower than that in the control group within 28-34 weeks (P <0.05). In 34-36 weeks, the incidence of maternal and infant adverse outcomes in the observation group The difference was statistically significant (P <0.05). There was no significant difference in the incidence of maternal and child adverse outcomes between the two groups in 36-37 weeks (P> 0.05). Conclusion: According to the actual situation of different gestational weeks and patients, different prenatal care should be taken to prevent the premature rupture of membranes in different preterm premature rupture of membranes to ensure the safety of mother and baby to the maximum extent. Premature infants born after delivery should be given targeted anti-infective treatment Measures to improve neonatal outcomes.